Treatment
Treatment literacy materials that cover the basics of hepatitis C treatment, research on efficacy in different key populations, and global treatment uptake.
Materials in this section
Health Economic Outcomes of a Minimal Monitoring Approach to Providing HCV Therapy
The ACTG A5360 trial demonstrated that HCV treatment without planned on-treatment monitoring is safe and effective. More
Integrated Hepatitis C Care in Syringe Service Programs Improves Outcomes for People Who Inject Drugs
Tailored models within syringe service programs can overcome barriers and improve HCV cure rates in underserved populations. More
HCV and HIV Coinfection: Decreasing Barriers to an HCV Cure With Use of a Simplified Treatment Algorithm
In 2023, the AASLD/IDSA treatment guidelines were updated to include the addition of the simplified algorithm in treatment-naive individuals with HIV/HCV coinfection. More
Hepatitis C Reinfection After DAA Therapy Linked to Substance Use, Comorbid HCC
In a large cohort of U.S. veterans, repeat viremia in adults with HCV who achieve SVR via DAA therapy may be more frequent among younger populations and those with a history of substance use or comorbid HCC. More
Understanding Barriers to Hepatitis C Antiviral Treatment in Low–Middle-Income Countries
Through a structured search of open access informational sources and an informal peer-reviewed literature review, HCV treatment barriers were identified, compiled, analysed and summarized as recommendations for LMICs. More
Subspecialty Physicians’ Perspectives on Barriers and Facilitators of Hepatitis C Treatment: A Qualitative Study
A study examined the perspectives of subspecialist physicians caring for substantial numbers of patients with HCV to better understand barriers and facilitators of HCV treatment. More
Unsuccessful Direct-Acting Antiviral Hepatitis C Treatment Among People With HIV: Findings From an International Cohort
A study examined characteristics that may indicate an increased probability of unsuccessful DAA HCV treatment. More
Barriers to and Impacts of Hepatitis C Treatment Among People Who Inject Drugs in Kenya: A Qualitative Study
In order for positive treatment outcomes to be sustained, HCV treatment programs must address the barriers patients face at multiple levels and implement system-level changes. More
Community Surveys Show Enthusiasm for Long-Acting HCV Cure Researc
People living with or at risk of hepatitis C virus, health care providers, and policymakers in low- and middle-income countries showed significant interest in a potential long-acting HCV cure, recent surveys have found. More
Immunodeficiency, Injection Drug Use Linked to Failed HCV Treatment in People with HIV
DAAs achieve a 95% success rate in treating HCV among HIV patients, but 5% experience unsuccessful treatment; Lower CD4 cell counts, HCV genotype 4, and recent injection drug use are linked to higher odds of unsuccessful treatment. More
